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Over the years, the absence of labels warning of the potential for toxicity has combined with the misconception of safety, leading to increasing misuse and abuse of ephedrine-containing products. Reports in the literature indicate abuse and misuse of all ephedrine products -- not just those marketed as dietary supplements but also those marketed as over-the-counter bronchodilators and decongestants. The increased availability and marketing of botanically derived ephedrine products since the passage of the Dietary Supplement Health and Education Act of 1994 contributed to the increasing number of adverse effects. (10)
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In traditional Chinese medicine, the herb ma huang (Ephedra sinica) contains ephedrine as its principal active constituent. The same is true of other herbal products containing extracts from Ephedra species. Nagayoshi Nagai was the first one to isolate ephedrine from Ephedra vulgaris in 1885. The substance called soma mentioned in old Hindu books such as the Rig Veda, may have been ephedra extract.
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In traditional Chinese medicine, the herb ma huang (Ephedra sinica) contains ephedrine as its principal active constituent. The same is true of other herbal products containing extracts from Ephedra species. Nagayoshi Nagai was the first one to isolate ephedrine from Ephedra vulgaris in 1885. The substance called soma mentioned in old Hindu books such as the Rig Veda, may have been ephedra extract.
Ephedrine is an ingredient used in certain over the counter medications (mostly nasal drops) to treat congestion and asthma. It's a stimulant, originally derived from an Asiatic shrub, and acts on the central nervous system. Recent reports suggest an increase in recreational misuse, in which the drug is sold as pills and is taken orally (by mouth).
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Ephedrine (EPH) is a sympathomimetic amine similar in structure to the synthetic derivatives amphetamine and methamphetamine. Ephedrine is commonly used as a stimulant, appetite suppressant, concentraton aid, decongestant and to treat hypotension associated with regional anaesthesia. Chemically, it is an alkaloid derived from various plants in the genus Ephedra (family Ephedraceae). It is most usually marketed in the hydrochloride and sulfate forms.
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